What is Melanotan 2?

Melanotan is a type of peptide called a melanotropin peptide which is an analog of the alpha-melanocyte stimulating hormone. This peptide is created and circulated within the skin. Synthetic Melanotan 2 is designed to tan and darken skin.


Melanotan 2 is a smaller and more potent than melanotan 1,it  targets more melanocortin receptors. This new peptide has a protective ring of amino acids which further seperates it from the linear style peptide of melanotan 1, which ensures better absorption.



How is it used?

Melanotan comes freeze dried and sealed in a multi-use sterile vile which is injected under the skin where it binds to melanocortin receptors. These receptors influence things like pigmentation, appetite, skin inflammation, and sexual function.

For practical purposes, this means that those that have fair skin, can achieve a rich, natural-looking tan even if they have an allergy to sunlight. This also means that these peptides make one of the best defenses against skin cancer available, all without spending years trying to develop a tan that will protect the skin.

When taking melanotan to darken the skin, it's important to remember that the tanning effect is a side effect of the peptide. When UV damage occurs in cells, the body responds by dispatching cells to repair this damage which then tan to protect the skin from further damage. This means that the user's body is not growing darker but is in fact tanning naturally with help from the peptide.




The Fitzpatrick Skin Chart

In order to fully measure the differences between fairer skin tones and darker ones, the Fitzpatrick skin type chart organizes them into one of six categories, making it easy to identify those who are at greater risk for skin cancer and make keeping track of tanning efforts easy.


Fitzpatrick Skin Type



Very fair. Always burn, never tans.


Fair skin, always burns but occasionally tans.


Medium skin, sometimes burns, always tans.


Olive skin, rarely burns, always tans.


Modestly pigmented brown skin. Never burns.


Definite pigment, never burns, always tans.


It should be noted that using melanotan is an ongoing therapy that will require a starting dosage and further maintenance after that until the user gets to the skin tone that they desire. This can take some time to develop but with a little patience and correct, safe dosage, excellent results can be achieved.

As a Weight Loss Treatment:
Because of it's effect on fat loss, tanning peptide is also used to aid in weight loss. Since the melanocortin system is important for controlling body weight, the use of melanotan increases oxidation in fatty acids which  improves insulin sensitivity, requiring less food to feel full and helps the body flush out fats.




Who uses melanotan? 
There are many who make use of melanotan: fitness enthusiasts and bodybuilders along with some athletes tend to use these types of peptides in order to increase the efficiency of their training regimen. This is because of the melanotan's ability to store energy within cells for easy access by the body, making it easier for the body to use them during training.

These peptides have been featured as everything from miracle compounds for weight loss because of their fat loss capabilities, however their use as a skin tanner has also been widely documented. Synthetic melanocortin has been show to help tan skin with the least amount of exposure to sunlight, making them extremely desirable for people who's flesh is ranked lower on the Fitzpatrick scale.

Because melanotan treatments are so effective (around 1,000 times more potent than naturally occurring melanotropin), many people think that they can begin a melanotan therapy and will be immune to the harmful effects of the sun. Those with blonde or red hair, especially those who are very pale should be careful and protect themselves with sunglasses, sunscreen and basic protections when going out in the sun for extended periods of time. Melanotan requires a bit of patience but users will see dramatic results in longer time.




Using Melanotan 2

Product Dosage and Considerations:
Melanotan 2 is transported and  sold in 10 miligram size. The reason for this is that lower doses ensure freshness and reduces the amount of travel time as well.

When reconstituted with sterile water, the melanotan 2 peptide becomes effective. Reconstituting tanning peptide is a part of the process for use and will require full attention to get proper results. 1-2ml sterile water will reconstitute the peptides. Diluting with more volume will improve dosing accuracy.

Please do not fall for the easier methods of taking Melanotan, injections is the only proper way of using this peptide. Many Internet suppliers will sell things like nasal sprays, pre-mixed peptide, oral pills and powders, few of which are what they came to be. There are a few positive reports of nasal spray experiences, however they tend to be fictitious or very unusual as the molecules contained in that form are too large to pass the nasal membrane.

Similarly, pills of this type are also quite useless because enzymes within the stomach will render the peptide inert.



How much to Buy:
Depending on the user's skin type, dosage for a full tanning season (3 months, typically), will vary. These are the most commonly advised dosages based upon skin type according to the Fitzpatrick Scale:
Appropriate 3 month Melanotan 2 dosage after loading phase:

Skin Type



30 to 50mg


20 to 30mg


10 to 20mg


As stated, these doses should last for a full tanning season. However if wanted Melanotan 2 peptide can be used all year round as there is no evidence of any long term side effects. Below, exact dosages will be measured out for individual applications and skin tones.


Getting Melanotan 2

Shipping and Handling: Melanotan peptides are durable and stable when shipped, surviving temperatures up to 98 degrees for almost a month or more. Thus, shipping them during summer months isn't a problem.
Peptides are very stable but after receiving them, they should be stored in the refrigerator to prevent possible spoilage.



Understanding Insulin Syringe:

Volume of insulin syringes is measured in IU (Internation Units)

100 IU  = 1 ML

10 IU = 0.1 ML

Calculating Dosage:

Add 1ml (100 IU) of sterile water to the peptide containing vial. Then the formula itself is fairly straight forward:

0.5mg Dosage:  5 IU (international units)
1mg Dosage   :  10 IU (international units)

The sterile water is added to the vial when the user is prepared to mix it, after which the water is injected into the peptide containing vial. The powder will dissolve into the water and should remain clear.

Typically, insulin needles are to be used to inject or mix the peptide. These needles are 29 to 30 gauge by ½” with a 1 CC (100 units) capacity. It's possible to use larger syringes, however getting precise measurements can be difficult.


Actual injection takes place by pinching the skin loose from the muscle and raising it so that a needle can be inserted between the skin and muscle. This is not a deep injection and melanotan should be injected in the fat layer of the skin.


Starting dose:
The first dosage should be fairly small, as little as .25mg in order to gauge the reaction of the user's body. This dosage should be taken before going to sleep for to let the peptides work overnight. Any problems that may arise will do so overnight, thus upon waking the user will know how their body will react. Ideally, the user should not feel anything.

Loading dose: 
If no adverse effects have shown up, it's fairly safe to assume that no problems will occur. After this initial span, loading dosages can be done once per day, consisting of an injection of 0.5 to 1mg. Those who have used doses in this range report getting good results and darkening skin pigmentation. Missing days will not make a lot of difference which will make it easier for people who travel or tend to forget things to keep dosing.


Maintenance dose:
Maintenance doses are taken once the desired pigmentation has been reached and requires much less frequent dosage than once a day. Normally maintenance dose is 2x or 3x your loading dose and is done once a week. Example: Sue was injecting 0.5mg every day and had a sunbed session every other day, after 8 days she was happy with her achieved skin tone, then she stopped taking melanotan daily and maintained her tan by injecting 1mg once a week day before sunbed session. This is maintenance dose, as the name implies, maintain the established color without darkening the skin further.


1. What is Melanotan?

Melanotan is a peptide that invigorates the natural secretion of melanin. This peptide is made and circulated inside the skin and when exposed to UV Rays makes the skin to get darker. Melanotan1 and 2 is an engineered analogue of this peptide which is designed to darken and tan the skin.

Melanin is a naturally secreted hormone which regulates the pigment in our skin. Put simply, the more the melanin in the body, the darker the pigment and subsequently the darker also the skin colour becomes.

2. Distinction between Melanotan 1 and 2

Melanotan II is a more intense peptide than its relative and furthermore works out to be a more moderate alternative. Melanotan I is a less intense peptide and it requires significantly more time for the impacts of it to be noticeable. It is then again viewed as a more secure alternative with less side effects.

3. Storage and Shelf Life of Melanotan

Both Melanotan I and II come as white freeze dried lyophilised powder contained in a sealed multi-use vial. They are transported and sold in 10 milligram size. The reason for this is that lower doses ensure freshness and reduces the amount of travel time as well.

Melanotan peptides are stable and durable when shipped, surviving about 37 degrees temperatures for around a month or more. Even during summer, this peptide can be shipped without hassles. Once they have been received, they ought to be put away in the refrigerator or better still, freezer to avert conceivable deterioration until ready to be mixed, which then the mixed Melanotan is stored in the refrigerator.

Many Internet suppliers will sell pre-mixed Melanotan however most of the time pre-mixed vials are not legitimate and you run the risk of infection or a compound that has lost a great deal of potency. All peptides should be delivered in lyophilized form. Lyophilized form is the most stable and durable form.



4. Administration


Melanotan 1 has a half-life of about 1 hour, what this translates to is that to receive the most in return, you need to inject twice in a day; morning and early afternoon or before UV exposure. It is likewise more advisable to dose each day – this sums a ton of injections.

Dosages recommended for Melanotan 1 begins from 1mg (500mcg twice per day) because of the lower symptoms connected with it. Following 2-4 days, you can increase to 1.5mg (750mcg twice per day) and stick to this. In the event that you wish to expand the dosage further, do it gradually

Melanotan 2 has an active life of 36 hours in your body; this permits you to be extremely adaptable with dosing. Dosages recommended begin at 250mcg consistently to help your body adjust to the peptide and minimize the reactions. You can proceed with these inconclusively in the event that you are meaning to do a regimen of low dosage.

On the off chance that you need to dose higher, following 2-4 days, at whatever point you feel good, up the dose to 500mcg. 500mcg is the most well-known dosage used by clients. You can increase this to about 1mg yet anything higher is for the most part not advised.



5. Which is better: Injections, Oral or Nasal?


Injection is the most effective way to administrate the peptide and results are seen the fastest and best. The nasal spray method is effective up to 30 – 40% because the nasal passages have poor absorption rate, you have to apply the nasal spray at least two to three times more than the injection. The injectable product of the Melanotan is very superior as compared to the nasal version. The nasal versions generally take four to five weeks for displaying the results appose to 10 days with the injection.



6. So How Long Before Results Are Seen?


There’s no fix time to see the outcomes. The vast majority of individuals get fabulous results after taking about 20mg of Melanotan2 while some see improvements only after about 6mg or more. On the average, one will only need between 7 to 10 days to show results after starting Melanotan.

Effect also depends largely on the type of skin. For a light-skinned user, it takes more time. Also exposure to UV determines how fast or otherwise.



7. Maintenance and Loading Dose


Dosages for maintenance begin once you have achieved your desired level of tan. It requires considerably less frequent dose than once every day. In spite of the fact that levels are diverse for everybody, all things considered 500mcg each 3 to 4 days or 1mg a week with a little measure of UV exposure will keep your tan maintained. It maintains the colour without further darkening the skin.



8. UV Exposure


Clinical studies have shown that Melanotan works without the need to combine it with any UV exposure, although results are achieved much faster when you incorporate 1-2 tanning sessions either the natural sun or ultraviolet with your Melanotan dosage.

The reason for this is while Melanotan significantly raises your levels of melanin, which is the brown pigment that gives your skin its tanned appearance, UV rays are an important factor in discharging your body’s melanin to the surrounding skin tissue.



9. Side Effects


There have been some side effects reported while using Melanotan 2, typically these effects appear during the first few days of dosing and will become increasingly less obvious as the body adjusts to the peptide. These effects include: nausea, appetite loss, drowsiness and increased sex drive. In order to combat nausea, an anti-histamine can be taken when injecting until the body gets used to it. But most common way to deal with this is to inject Melanotan before bed, this is also beneficial to combat any drowsiness.

You may also experience freckles appearing, this is the Melanotan darkening any freckles you may not have been able to see before. It is advisable to avoid this side effect to keep your dosage low and do not exceed 0.5mg per day.

If you start to notice freckles appearing lower your dosage amount and build your tan slower. Any freckles/moles that have darkened during the usage of Melanotan II will usually fade upon cessation of use; however, the time for this to occur will be different for each user.



10. Avoid Burning


Though tans protect the skin from burning, the Melanotan peptide will not protect the skin. This makes it important not to overexpose yourself when first starting the therapy. You should start only with the amount of exposure that your skin can handle without burning.



Anyone who has ever wanted to tan themselves safely and quickly will find these peptides a fantastic alternative to more costly and potentially dangerous supplements, hours in the sun or dubious spray on tans that never look quite right.
Melanotan 2 is one of the most versatile and useful peptides available on the market today and, with a little patience, can be a cornerstone for any serious tanning regimen or weight loss program when taken correctly.